Hematin administration to an adult with lead intoxication

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Hematin administration to an adult with lead intoxication.

Lead poisoning and acute intermittent porphyria (AIP) may exhibit similar neurologic manifestations, and they have in common elevated excretion of urinary aminolevulinic acid (ALA). Despite their similarities, the possible pathophysiologic connection between AIP and lead poisoning in not known. Because intravenous hematin administration has produced biochemical improvement in AIP, a hematin tri...

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Erythrocyte fluorescence and lead intoxication.

Blood samples from people exposed to inorganic lead were examined by fluorescence microscopy for excess erythrocyte porphyrin. With continued lead absorption, fluorescent erythrocytes appeared in the circulation of workers handling this metal or its compounds, and they progressively increased in number and brilliance. These changes ensued if the blood lead concentration was maintained above 2-4...

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Behavioral Assessment of Lead Intoxication*

Current questions about lead exposure focus on the consequences of levels too low to have erupted into blatantly discernible defects. The present paper addresses two sets of interrelated problems derived from this issue. One is how to define the behavioral consequences of asymptomatic lead absorption, and the second focuses on behavioral assessment procedures. Current primary prevention program...

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Catatonic syndrome associated with lead intoxication: a case report

INTRODUCTION Little is known about catatonia associated with lead intoxication. CASE PRESENTATION A retired printing house worker man presented with one week history of refusal to eat and mutism. He was treated with possible diagnosis of catatonia with administration of Lorazepam 3 mg P.O. daily. Significant improvement occurred after 48 hours. In further examinations, there was no evidence o...

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Lead intoxication associated with chewing plastic wire coating--Ohio.

Lead Intoxication — Continued In December 1991, a venous blood lead level (BLL) of 50 μg/dL was detected in a 46-year-old Ohio man during a routine pre-employment examination. He was referred to a university-based pharmacology and toxicology clinic for further evaluation; clinic physicians investigated the case. Although a repeat BLL obtained 1 month later was 51 μg/dL, he reported no exposure ...

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ژورنال

عنوان ژورنال: Blood

سال: 1979

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v53.5.1007.1007